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|
Factors
|
OS
|
TTR
|
|---|
|
Univariate P value
|
Multivariate
|
Univariate P value
|
Multivariate
|
|---|
|
HR
|
95% CI
|
P value
|
HR
|
95% CI
|
P value
|
|---|
|
Hepatitis B e antigen: positive versus negative
|
0.038
|
1.547
|
1.033–2.318
|
0.034
|
0.013
|
1.709
|
1.169–2.498
|
0.006
|
|
AFP (≤ 400 versus > 400 ng/ml)
|
0.024
| | |
NS
|
0.005
| | |
NS
|
|
Tumor differentiation: low versus high
|
0.027
|
1.920
|
1.192–3.095
|
0.007
|
0.235
| | |
NA
|
|
Vascular invasión(yes vs. no)
|
< 0.001
| | |
NS
|
0.001
| | |
NS
|
|
Tumor size (≤ 5 vs. > 5 cm)
|
< 0.001
|
2.963
|
1.864–4.710
|
< 0.001
|
< 0.001
|
2.108
|
1.392–3.193
|
< 0.001
|
|
Tumor number (single versus. multiple)
|
0.004
| | |
NS
|
0.008
| | |
NS
|
|
UICC TNM stage (I vs. II vs. IIIA)
|
< 0.001
|
1.703
|
1.274–2.275
|
< 0.001
|
< 0.001
|
1.548
|
1.186–2.022
|
0.001
|
|
STOML2 (low vs. high)
|
0.001
|
1.596
|
1.057–2.410
|
0.026
|
0.003
|
1.638
|
1.120–2.395
|
0.011
|
- OS overall survival, TTR time to recurrence, CI, confidence interval, HR hazard ratio, NA not adopted, NS not significant, AFP α-fetoprotein, UICC International Union Against Cancer, TNM tumor-node-metastasis, STOML2 Stomatin-like protein 2
